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Cytosolic BolA Plays a Repressive Role in the Tolerance against Excess Iron and MV-Induced Oxidative Stress in Plants.

Identifieur interne : 000566 ( Main/Exploration ); précédent : 000565; suivant : 000567

Cytosolic BolA Plays a Repressive Role in the Tolerance against Excess Iron and MV-Induced Oxidative Stress in Plants.

Auteurs : Lu Qin [République populaire de Chine] ; Meihuan Wang [République populaire de Chine] ; Jia Zuo [République populaire de Chine] ; Xiangyang Feng [République populaire de Chine] ; Xuejiao Liang [République populaire de Chine] ; Zhigeng Wu [République populaire de Chine] ; Hong Ye [République populaire de Chine]

Source :

RBID : pubmed:25928219

Descripteurs français

English descriptors

Abstract

The BolA-like protein is present in all eukaryotes, and it is able to form complex with monothiol glutaredoxin of the same subcellular compartments, suggesting that the BolA-like protein has essential function in eukaryotes, and that the function is associated with its partner glutaredoxin. Some studies have indicated a role for BolA proteins in Fe-S cluster synthesis or in redox homeostasis. However, the physiological function of BolA proteins remains to be elucidated. Here, we report the characterization of an insertion mutant of BolA3 in Arabidopsis. Among the four AtBolA proteins found in Arabidopsis, the AtBolA3 was the only BolA located in the cytosol of plant cells. It was highly expressed in roots. AtBolA3 was able to interact with the cytosolic monothiol glutaredoxin, AtGRXS17. The bola3 mutant did not show any notable phenotype under normal growth condition, but rather grew better than wild type under some stresses. The bola3 mutant was more tolerant to excess iron and the MV-induced oxidative stress than wild type. It displayed no necrosis in leaves, developed longer roots, accumulated more iron and higher Fe-S protein activities in roots. In addition, the mutant possessed a more potent antioxidant defense to scavenge ROS species. Taken together, our data indicated that the cytosolic AtBolA3 has a suppressive role in the tolerance to excess iron and the MV-induced oxidative stress in plants. AtBolA3 seems to be a repressor under some stress conditions.

DOI: 10.1371/journal.pone.0124887
PubMed: 25928219
PubMed Central: PMC4415784


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<term>Amino Acid Sequence (MeSH)</term>
<term>Arabidopsis Proteins (chemistry)</term>
<term>Arabidopsis Proteins (genetics)</term>
<term>Arabidopsis Proteins (metabolism)</term>
<term>Cytosol (metabolism)</term>
<term>DNA-Binding Proteins (chemistry)</term>
<term>DNA-Binding Proteins (genetics)</term>
<term>DNA-Binding Proteins (metabolism)</term>
<term>Gene Expression Regulation, Plant (MeSH)</term>
<term>Intracellular Space (metabolism)</term>
<term>Iron (metabolism)</term>
<term>Iron Overload (genetics)</term>
<term>Iron Overload (metabolism)</term>
<term>Molecular Sequence Data (MeSH)</term>
<term>Mutagenesis, Insertional (MeSH)</term>
<term>Organ Specificity (genetics)</term>
<term>Oxidative Stress (drug effects)</term>
<term>Oxidative Stress (genetics)</term>
<term>Paraquat (pharmacology)</term>
<term>Phenotype (MeSH)</term>
<term>Plant Roots (metabolism)</term>
<term>Plants (genetics)</term>
<term>Plants (metabolism)</term>
<term>Protein Transport (MeSH)</term>
<term>Sequence Alignment (MeSH)</term>
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<term>Adaptation biologique (MeSH)</term>
<term>Alignement de séquences (MeSH)</term>
<term>Cytosol (métabolisme)</term>
<term>Données de séquences moléculaires (MeSH)</term>
<term>Espace intracellulaire (métabolisme)</term>
<term>Fer (métabolisme)</term>
<term>Mutagenèse par insertion (MeSH)</term>
<term>Paraquat (pharmacologie)</term>
<term>Phénotype (MeSH)</term>
<term>Plantes (génétique)</term>
<term>Plantes (métabolisme)</term>
<term>Protéines d'Arabidopsis (composition chimique)</term>
<term>Protéines d'Arabidopsis (génétique)</term>
<term>Protéines d'Arabidopsis (métabolisme)</term>
<term>Protéines de liaison à l'ADN (composition chimique)</term>
<term>Protéines de liaison à l'ADN (génétique)</term>
<term>Protéines de liaison à l'ADN (métabolisme)</term>
<term>Racines de plante (métabolisme)</term>
<term>Régulation de l'expression des gènes végétaux (MeSH)</term>
<term>Spécificité d'organe (génétique)</term>
<term>Stress oxydatif (effets des médicaments et des substances chimiques)</term>
<term>Stress oxydatif (génétique)</term>
<term>Surcharge en fer (génétique)</term>
<term>Surcharge en fer (métabolisme)</term>
<term>Séquence d'acides aminés (MeSH)</term>
<term>Transport des protéines (MeSH)</term>
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<term>Arabidopsis Proteins</term>
<term>DNA-Binding Proteins</term>
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<term>Arabidopsis Proteins</term>
<term>DNA-Binding Proteins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en">
<term>Arabidopsis Proteins</term>
<term>DNA-Binding Proteins</term>
<term>Iron</term>
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<term>Protéines d'Arabidopsis</term>
<term>Protéines de liaison à l'ADN</term>
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<term>Oxidative Stress</term>
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<term>Stress oxydatif</term>
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<term>Organ Specificity</term>
<term>Oxidative Stress</term>
<term>Plants</term>
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<term>Protéines d'Arabidopsis</term>
<term>Protéines de liaison à l'ADN</term>
<term>Spécificité d'organe</term>
<term>Stress oxydatif</term>
<term>Surcharge en fer</term>
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<keywords scheme="MESH" qualifier="metabolism" xml:lang="en">
<term>Cytosol</term>
<term>Intracellular Space</term>
<term>Iron Overload</term>
<term>Plant Roots</term>
<term>Plants</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr">
<term>Cytosol</term>
<term>Espace intracellulaire</term>
<term>Fer</term>
<term>Plantes</term>
<term>Protéines d'Arabidopsis</term>
<term>Protéines de liaison à l'ADN</term>
<term>Racines de plante</term>
<term>Surcharge en fer</term>
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<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr">
<term>Paraquat</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en">
<term>Paraquat</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adaptation, Biological</term>
<term>Amino Acid Sequence</term>
<term>Gene Expression Regulation, Plant</term>
<term>Molecular Sequence Data</term>
<term>Mutagenesis, Insertional</term>
<term>Phenotype</term>
<term>Protein Transport</term>
<term>Sequence Alignment</term>
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<term>Alignement de séquences</term>
<term>Données de séquences moléculaires</term>
<term>Mutagenèse par insertion</term>
<term>Phénotype</term>
<term>Régulation de l'expression des gènes végétaux</term>
<term>Séquence d'acides aminés</term>
<term>Transport des protéines</term>
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<front>
<div type="abstract" xml:lang="en">The BolA-like protein is present in all eukaryotes, and it is able to form complex with monothiol glutaredoxin of the same subcellular compartments, suggesting that the BolA-like protein has essential function in eukaryotes, and that the function is associated with its partner glutaredoxin. Some studies have indicated a role for BolA proteins in Fe-S cluster synthesis or in redox homeostasis. However, the physiological function of BolA proteins remains to be elucidated. Here, we report the characterization of an insertion mutant of BolA3 in Arabidopsis. Among the four AtBolA proteins found in Arabidopsis, the AtBolA3 was the only BolA located in the cytosol of plant cells. It was highly expressed in roots. AtBolA3 was able to interact with the cytosolic monothiol glutaredoxin, AtGRXS17. The bola3 mutant did not show any notable phenotype under normal growth condition, but rather grew better than wild type under some stresses. The bola3 mutant was more tolerant to excess iron and the MV-induced oxidative stress than wild type. It displayed no necrosis in leaves, developed longer roots, accumulated more iron and higher Fe-S protein activities in roots. In addition, the mutant possessed a more potent antioxidant defense to scavenge ROS species. Taken together, our data indicated that the cytosolic AtBolA3 has a suppressive role in the tolerance to excess iron and the MV-induced oxidative stress in plants. AtBolA3 seems to be a repressor under some stress conditions. </div>
</front>
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<AbstractText>The BolA-like protein is present in all eukaryotes, and it is able to form complex with monothiol glutaredoxin of the same subcellular compartments, suggesting that the BolA-like protein has essential function in eukaryotes, and that the function is associated with its partner glutaredoxin. Some studies have indicated a role for BolA proteins in Fe-S cluster synthesis or in redox homeostasis. However, the physiological function of BolA proteins remains to be elucidated. Here, we report the characterization of an insertion mutant of BolA3 in Arabidopsis. Among the four AtBolA proteins found in Arabidopsis, the AtBolA3 was the only BolA located in the cytosol of plant cells. It was highly expressed in roots. AtBolA3 was able to interact with the cytosolic monothiol glutaredoxin, AtGRXS17. The bola3 mutant did not show any notable phenotype under normal growth condition, but rather grew better than wild type under some stresses. The bola3 mutant was more tolerant to excess iron and the MV-induced oxidative stress than wild type. It displayed no necrosis in leaves, developed longer roots, accumulated more iron and higher Fe-S protein activities in roots. In addition, the mutant possessed a more potent antioxidant defense to scavenge ROS species. Taken together, our data indicated that the cytosolic AtBolA3 has a suppressive role in the tolerance to excess iron and the MV-induced oxidative stress in plants. AtBolA3 seems to be a repressor under some stress conditions. </AbstractText>
</Abstract>
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<ReferenceList>
<Reference>
<Citation>J Biol Chem. 2011 Jan 7;286(1):867-76</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">20978135</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Plant Physiol. 1996 Mar;110(3):781-789</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">12226218</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Trends Biochem Sci. 2010 Jan;35(1):43-52</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">19811920</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Trends Plant Sci. 2005 Jul;10(7):324-31</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">15951221</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Plant Sci. 2000 Sep 8;158(1-2):71-76</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">10996246</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Annu Rev Biochem. 2008;77:669-700</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">18366324</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Biochemistry. 2012 Jun 5;51(22):4377-89</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">22583368</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Mol Plant. 2014 Jan;7(1):187-205</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">24203231</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Plant J. 1998 Dec;16(6):735-43</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">10069079</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>J Clin Invest. 2011 Jan;121(1):212-25</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">21123948</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Antioxid Redox Signal. 2013 Jan 10;18(2):129-38</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">22746225</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Biochemistry. 2009 Oct 13;48(40):9569-81</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">19715344</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Plant Physiol. 2011 Apr;155(4):1893-907</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">21325567</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Plant Physiol. 2009 Oct;151(2):590-602</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">19710232</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>EMBO J. 2008 Apr 9;27(7):1122-33</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">18354500</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>J Biol Chem. 2006 Mar 31;281(13):8958-69</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">16455656</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Trends Plant Sci. 2011 Apr;16(4):218-26</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">21257336</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Science. 2003 Dec 5;302(5651):1727-36</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">14605208</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Biochemistry. 2012 Feb 28;51(8):1687-96</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">22309771</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Trends Plant Sci. 2009 May;14(5):280-5</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">19375375</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>EMBO J. 1987 Dec 20;6(13):3901-7</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">3327686</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Anal Biochem. 1987 Mar;161(2):559-66</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">3034103</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>New Phytol. 2013 Sep;199(4):925-35</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">23734982</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Biochem Biophys Res Commun. 1994 Jul 29;202(2):1113-9</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">8048925</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Mol Microbiol. 1999 May;32(4):789-98</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">10361282</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Annu Rev Plant Biol. 2012;63:131-52</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">22404471</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Front Plant Sci. 2013 Jul 24;4:259</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">23898337</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Cell Mol Life Sci. 2007 Jun;64(12):1518-30</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">17415523</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>J Biol Chem. 2011 Jun 10;286(23):20398-406</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">21515673</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Plant Cell. 1999 Dec;11(12):2283-90</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">10590158</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>FEBS J. 2011 Jul;278(14):2525-39</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">21575136</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Nature. 2009 Aug 13;460(7257):831-8</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">19675643</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Am J Hum Genet. 2011 Oct 7;89(4):486-95</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">21944046</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>J Biol Chem. 2008 Apr 18;283(16):10276-86</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">18281282</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Plant Biotechnol J. 2012 Oct;10(8):945-55</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">22762155</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>J Biol Chem. 2006 Jun 30;281(26):17661-9</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">16648636</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Nat Chem Biol. 2009 May;5(5):333-40</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">19377460</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Curr Opin Plant Biol. 2009 Jun;12(3):347-57</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">19481497</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>J Bacteriol. 1988 Nov;170(11):5169-76</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">3053647</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
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